<!DOCTYPE html>
<html lang="en">
<head>
  <meta charset="UTF-8">
  <meta name="viewport" content="width=device-width, initial-scale=1.0">
  <title>Document</title>
  <style>
    * {
      margin: 0;
      padding: 0;
    }
    .wrapper {
      display: flex;
      flex-direction: row;
      height: 200px;
      /* flex-direction: row-reverse; */
      /* flex-direction: column; */
      /* flex-direction: column-reverse; */
      width: 500px;
      justify-content: space-around;
      align-content: space-between;
      background: burlywood;
      flex-wrap: wrap;
    }
    .wrapper .item {
      background-color: red;
      width: 200px;
    }
    .wrapper .item:nth-child(1) {
      flex-grow: 1;
    }
    .wrapper .item:last-child {
      margin-left: 20px;
    }
  </style>
</head>
<body>
  <div class="wrapper">
    <div class="item">flex1</div>
    <div class="item">flex2</div>
    <!-- <div class="item">flex3</div>
    <div class="item">flex4</div>
    <div class="item">flex5</div> -->
  </div>
</body>
</html>